Which Type Of Oil Should You Be Injecting Testosterone Therapy With?

When it comes to testosterone administration, several oil bases are used in compounding. For those unfamiliar, there are three traditional oil bases used in testosterone compounding: sesame seed oil, cottonseed oil, and grapeseed oil. Each differs significantly regarding the inflammatory response they can cause in our bodies.
At MHI, we have typically prescribed testosterone in grapeseed oil due to its low viscosity and minimal inflammatory response. It’s important to understand that more inflammation leads to increased water retention in your body.
Let’s examine these three base types of oils used in testosterone therapy and introduce the newest option gaining popularity: “MCT” oil base.

Cottonseed Oil

This oil base is used in 99% of all testosterone brand names. It is the most inflammatory of all the oils. Cottonseed is not food nor a substance that is truly recognized by our bodies, hence our body’s negative response. It is well known that cottonseed oil can cause health problems like infertility, liver damage, pregnancy problems, respiratory distress, and anorexia to name a few, all while being far more expensive than the compounded versions. For these reasons we certainly find this oil base to be the least desirable option.

Sesame Seed Oil

This oil is the most commonly used by compounding pharmacies. With the years we’ve seen that, by default, compounding pharmacies use this base unless requested otherwise. We reckon this has to do with production and cost. In terms of its inflammatory response we find this oil base to be in 2nd place.

Grapeseed Oil

In regards to overall health, this seed extract provides the body with many health benefits like improved blood flow, can reduce oxidative damage, and reduction of blood pressure. Mainly though, we know this oil-base is the least inflammatory injectable oil in the industry which is why we make it our default choice on all our testosterone prescriptions. Though now, a new oil has found the spotlight – Medium Chain Triglycerides oil or “MCT oil”.

MCT Oil & Testosterone Therapy Injections

MCT oil not only has potent anti-inflammatory properties but also has antimicrobial and antifungal effects. In food, MCT oil has been shown to support weight and fat loss. Moreover, MCT oil can also increase the production of heart-protective HDL or “good” cholesterol. It can even significantly reduce C-reactive protein (CRP), which is an inflammatory marker that increases the risk of heart disease. MCT oil is easy to absorb and use, it offers the digestive system a break and is often a fantastic choice for those who struggle with digestive problems, fat absorption, or lack a gallbladder. Judging from the results we’ve seen with our patients this is our preferred oil base for injectable testosterone administration.

We hope this blog has been useful. If you have any questions about this subject please make sure to get with your assigned care coordinator and ask him any additional questions you may have. Also, be sure to ask about our new tri-blend (Cypionate/Enanthate/Propionate) injectable testosterone in MCT oil.

To learn more about TRT go to our Testosterone Replacement Therapy page. To Schedule your free consultation contact us now.